BIOCHEMISTRY INTERVIEW QUESTIONS

Most Important Frequently Asked Biochemistry Interview Questions

Interview Quesions on Biochemistry

1. Question 1. Give The Example For Electrophilic Substitution Reaction.

   Answer :

   The species, which accepts the electrons, are called Electrophilles (or) Electrophilic reagents.

   When the atom (or) group of atoms present in the organic compound is replaced by another atom (or) group of atoms (electrophilic) is called electrophilic substitution reaction.

2. Question 2. What Is Addition Reaction?

   Answer :

   When atoms (or) group of atoms are added, to form more saturated compound it is called addition reaction.

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3. Question 3. How Do You Define Free Radical Addition Reaction?give An Example.

   Answer :

   When unsaturated compounds undergo addition reactions with free radicals,it is called free radical addition reaction.

   Ex; CH3­CH = CH2+HBr———–> CH3­CH2­CH2Br

4. Question 4. What Is Nucleophilic Addition Reaction?

   Answer :

   When the attacking species during the addition reaction is Nucleophilic, it is nucleophilic addition reaction.
    Ex; Acetaldehyde cynohydrin

5. Question 5. What Is Electrophilic Addition Reaction?

   Answer :

   When the attacking species during the addition reaction is Electrophile, it is called electrophilic addition reaction. 

   Ex; (+) (­) (+) (­) (+) (­)

   CH2Br­CH2BràH2C­CH2+BrBr­àH2C=CH2+Br2­

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6. Question 6. What Are The Favourable Conditions For Formation Of Cat Ions?

   Answer :

   1. Low Ionisational potential.
   2. Lesser Charge.
   3. More atomic size of atoms forms cations easily.
   4. Ions having Inert gases configuration formed easily.

7. Question 7. What Are The Favourable Conditions For Formation Of Anions?

   Answer :

   • High Electron affinity
   • Small size
   • Less charge of an atoms form anion more easily

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8. Question 8. Define Lattice Energy.

   Answer :

   The energy released when one mole of ionic crystal is formed by the combination of the corresponding gaseous (+ve) and (­ve) ions brought from infinite distance is called lattice energy.

9. Question 9. What Happens If Lattice Energy Increases?

   Answer :

   • The Strength of ionic bond
   • Stability of the Ionic compound
   • Ease of formation of the Ionic bond Increases

10. Question 10. What Is Sublimation Energy?

    Answer :

    The amount of energy required to convert one mole of solid substance to vapor state is called Sublimation energy

11. Question 11. What Can You Calculate By Selecting Born-­haber Cycle?

    Answer :

    Born­Haber cycle is useful for calculation of lattice energy, heat of reaction and electron affinity.

12. Question 12. How Can Energy Change In The Formation Of Nacl Be Determined?

    Answer :

    With the help of Born Haber’s cycle.

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13. Question 13. What Is The Relation Between Reaction Taking Place In One Of The Several Stages And The Total Amount Of Energy Liberated In The Reaction?

    Answer :

    The relation between reaction taking place in one of the several stages and the total amount of energy liberated in the reaction is same.

14. Question 14. Define Limiting Radius.

    Answer :

    The ratio between the radius of cation and the radius of anion is called Limiting radius.

15. Question 15. What Is Co­-ordination Number?

    Answer :

    The number of appositively charged ions surrounded a particular ion in an ionic crystal lattice is called co­-ordination number.

16. Question 16. What Is Structure Of Nacl And Give The Co­-ordination Number Of Nacl?

    Answer :

    The structure of Nacl is face centered Cubic and Co­-ordination number of Nacl is 6.

17. Question 17. What Is The Structure Of Cscl And Give The Co­-ordination Number Of Cscl?

    Answer :

    The structure of cscl is Body Centered Cubic and the Co-ordination number of CsCl is 8.

18. Question 18. Ionic Compound Does Not Show The Property Of Space Isomerism, Give The Reason?

    Answer :

    Ionic bond is Electrostatic. It is non directional, so Ionic compounds does not show the property of Space Isomerism.

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19. Question 19. In Double Bond, How Many Sigma And Pi Bonds Are Present In It?

    Answer :

    Double bond = 1 Sigma bond and one Pi bond Among sigma and Pi bonds which is the stronger one Sigma bond is Stronger than pi bond

20. Question 20. Define Polar Covalent Bond

    Answer :

    The covalent bond formed by the unequal sharing of electrons between the two atoms is called polar covalent bond.

21. Question 21. What Is Dipole?

    Answer :

    In polar covalent molecule, one atom gets positive charge and the other one gets negative charge hence called dipole.

22. Question 22. Covalent Bond Is Directional Therefore Which Covalent Property Is Shown?

    Answer :

    Space Isomerism

23. Question 23. Which Theory Explains The Paramagnetic Nature Of Oxygen?who Proposed It?

    Answer :

    Molecular orbital theory, proposed by Hunds and Mulliken

24. Question 24. Define Co-­ordination Covalent Bond.

    Answer :

    Co­ordination covalent bond is formed by the mutual sharing of pair of electrons between two atoms contributed by only one of the combining atoms.

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25. Question 25. What Does One Debye Equals?

    Answer :

    10­18 e.s.u – Cm

26. Question 26. Which Property Among The Following Generally Decreases From Top To Bottom In A Group 1a?

    Answer :

    Electropositive, Density,Basic nature, classical reactivity Electro affinity, electro negativity, Ionisational potential,melting and boiling points decreases from top to bottom in a group 1A from lithium to caesium.

27. Question 27. Which Property Among The Following Generally Increases From Top To Bottom In A Group 1a?

    Answer :

    Electropositive, Density,Basic nature, classical reactivity Electropositive, Density, Basic nature, classical reactivity, and solubility generally increase from top to bottom from lithium to caesium.

28. Question 28. Which Element In 1a Group Does Not Form Peroxides?

    Answer :

    Lithium

29. Question 29. Which Metal Is More Metallic In Nature Among 1a Group Elements?

    Answer :

    Francium.

30. Question 30. Define Bond Energy.

    Answer :

    The amount of energy released when one mole of bonds are formed between the corresponding gaseous atoms is called Bond energy.

31. Question 31. Define The Phenomenon Resonance.

    Answer :

    When a molecule is represented by two or more nearly equal structures, which differ in the arrangement of electrons, then the molecule is said to exhibit resonance.

32. Question 32. Which Group Of Elements Is Called Alkaline Earth Metals?

    Answer :

    1st A group because the oxides and hydrides are alkaline in nature Among 1A group elements why the element lithium is the most powerful, reducing agent in equivalent state Due to its low sublimation and hydration energy.

33. Question 33. Define Bond Angle.

    Answer :

    The angle between the lines joining the nuclei of the bonded atom with a central atom is called bond angle.

34. Question 34. What Is The Order Of C­h Bond Length In C2h6 And C2h4 And C2h2?

    Answer :

    c2h6>c2h4 >c2h2

35. Question 35. What Are The Units Of Bond Length?

    Answer :

    The intermolecular distance between the bonded atoms in a molecule is called bond length and the units are Angstrom units (A0).

36. Question 36. Who Proposed Vsepr Theory? What Does It Explain?

    Answer :

    VSEPR theory was proposed by Sedgwick and Powell. It explains the shapes of polyatomic molecules.

37. Question 37. In Water Molecule The Bond Angle Decreases From 109.28 To 104.5, Why This Does Happens?

    Answer :

    The repulsion between lone pair and lone pair electrons In NH3 molecule, the bond angle decreases from 109.28 to 107.3 why does it happen.The more repulsion between lone pair and bond pair.

38. Question 38. Define Hybridization.

    Answer :

    The distribution of electrons into Hybrid orbitals is as per the Paulis Exclusion principle and the Hunds rule of Maximum Multiplicity.

39. Question 39. Alkaline Metals When Dissolved In Ammonium (nh3) Act As Better Conductor And Better Reducing Agent What Is The Reason Behind It?

    Answer :

    Due to formation of solvated or Ammoniated electrons

40. Question 40. Which Element In 1a Group Is Lighter Than Water?

    Answer :

    Lithium, Sodium, and potassium

41. Question 41. What Are The Raw Materials Used For The Precipitation Of Na2co3 By Solvay Ammonium Process?

    Answer :

    Sodium Chloride, limestone and ammonia.

42. Question 42. Give The Chemical Formula For Borax.

    Answer :

    (Na2) B4 (O7) .10(H2) O

43. Question 43. Give The Formula For Peral Ash.

    Answer :

    The formula for Peral Ash is K2CO3.

44. Question 44. What Are The Compounds Used For Extraction Of Gold And Silver?

    Answer :

    NaCN and KCN

45. Question 45. What Is The Formula Of Hypo In Oxidation State Of Sulphur?

    Answer :

    The formula of Sodium Thio Sulphate is Na2S2O3. H2O is called as hypo Oxidation state of Sulphur in it is +6 0r ­2.

46. Question 46. How Many Elements Are There In 3d­ Series Of First Transition Series?

    Answer :

    Ten elements from Sc (Z=21) to Zn (z=30) or {Sc –scandium to Zn (zinc)}.

47. Question 47. Why Nitrogen Cannot Form Penta Halides?

    Answer :

    Because of the absence of d­orbital in its valency shells Ortho Phosphoric acid is. Give oxidation no of phosphorous in it.

    H3PO4­ortho phosphoric acid Oxidation state of phosphorous is +5.

48. Question 48. What Is The Super Phosphate Of Lime?

    Answer :

    Ca (H2Po4)2 caSO4. 2H2O. Super phosphate of lime is also called as Calcium super Phosphate Sixth group elements are called as.Chalcogens (ore forming elements)

49. Question 49. Which Elements Are Present In Electron?

    Answer :

    Electron consist of 95 % mg, 5% Zn.

50. Question 50. Which Are The Most Abundant Metal And Third Abundant Element In The Earth Crust?

    Answer :

    Aluminium (Al) (7.28%)

51. Question 51. What Is Inert Pair Effect?

    Answer :

    The reluctances of ns electrons in the participation of bond formation is called inert pair effect.

52. Question 52. What Does Ammonal Contain? For What Purpose It Is Used.

    Answer :

    It is a mixture of ammonium nitrate and aluminium powder is called ammonal, which is used as an explosive in Bombs.

53. Question 53. What Is Thermite Mixture?

    Answer :

    A mixture of Fe2O3 and ammonium powder in 3:1 ratio is called Thermite mixture.

54. Question 54. Which Univalent Element Cannot Form Alums And Why?

    Answer :

    Lithium (Li+) does not produce alums because of its very small size.

55. Question 55. How Do We Prepare Diborane?

    Answer :

    The Diborane (B2H6) is prepared by the reduction of BCl3 with aluminium hydride B2H6+3AlCl3+3LiClà4 BCl3+3LiAlH4

56. Question 56. What Is Banana Bond? Diborane Contains How Many Banana Bonds

    Answer :

    In Diborane B­H­B, bridge, which is formed by the sharing of two electrons, is called banana bond or Tau bond Diborane contains two banana bonds.

57. Question 57. How Much Amount Of Energy Is Required To Break The Triple Bond In Nitrogen Molecule?

    Answer :

    225 Kcal/mole or 945.4 KJ/mole

58. Question 58. How Many Sigma And Pi Bonds Are Present In Nitrogen Formula?

    Answer :

    Each nitrogen molecule contain one sigma and 2 Pi bonds

59. Question 59. What Are The Important Sources Of Phosphorus?

    Answer :

    Sources of Phosphorous are Phosphate rocks

    • Flourapatite {2Ca3 (PO4)2 CaF2}
    • Phosphorite {Ca3 (PO4)2}

60. Question 60. What Is The Molecular Formula, Structure, And Bond Angle Of Phosphorous?

    Answer :

    • P4­ Phosphorous molecule (Tetra atomic)
    • Structure ­- Tetrahedral
    • Bond angle – (60 degrees)

Topic: Biochemistry Interview Questions
Interview Quesions on Biochemistry